SPIR

"SPIR (Standard Portable Intermediate Representation) was initially developed for use by OpenCL and SPIR versions 1.2 and 2.0 were based on LLVM. SPIR has now evolved into a true cross-API standard that is fully defined by Khronos with native support for shader and kernel features – called SPIR-V.

SPIR-V is the first open standard, cross-API intermediate language for natively representing parallel compute and graphics and is incorporated as part of the core specification of both OpenCL 2.1 and OpenCL 2.2 and the new Vulkan graphics and compute API.

SPIR-V exposes the machine model for OpenCL 1.2, 2.0, 2.1, 2.2 and Vulkan - including full flow control, and graphics and parallel constructs not supported in LLVM. SPIR-V also supports OpenCL C and OpenCL C++ kernel languages as well as the GLSL shader language for Vulkan (under development).

SPIR-V 1.1, launched in parallel with OpenCL 2.2, now supports all the kernel language features of OpenCL C++ in OpenCL 2.2, including initializer and finalizer function execution modes to support constructors and destructors. SPIR-V 1.1 also enhances the expressiveness of kernel programs by supporting named barriers, subgroup execution, and program scope pipes."

https://www.khronos.org/spir

https://www.khronos.org/registry/spir-v/

Python

spirv-tools - https://github.com/kristerw/spirv-tools

Python API and tools for manipulating and optimizing SPIR-V.